She felt the effect within days. “I was irritable and enraged basically from the moment I went off,” she emailed me, adding (condescendingly, I suspected), “whereas you seemed more relaxed than I’d ever seen you.” Now that she was off Lexapro, she reported, “I no longer feel inclined to hang out. And when I am hanging out (for example with my family, who want me back on the meds), I feel that terrible itch to get back home and start doing something worthwhile.”